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Hi readers,

One of the biggest privileges of building Feline Business Brief is getting to speak with passionate, driven people who are shaping the future of feline care.

But it’s not every day that we get to interview one of the most influential figures in global feline health.

This week, we bring you an in-depth interview with Jon Ayers, former longtime CEO of U.S. veterinary diagnostics giant IDEXX Laboratories.

Ayers is also on the board of CATalyst Council, which accelerates innovation in feline care, and Chair of Panthera, a global non-profit dedicated to conserving the 40 species of wild cats.

We had so much to talk about that we're publishing in two parts! Read on for Part 1. Part 2 (Q&A transcript) comes out on Friday.

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Former IDEXX CEO Jon Ayers: How AI will reshape feline care

Jon Ayers at his Fort Lauderdale home

“People are waking up to the fact that feline veterinary medicine is a growth factor,” said Jon Ayers, former longtime CEO of IDEXX Laboratories.

Feline health, which has long lagged that of dogs, is entering a transformative period. This is driven mainly by the sudden maturity of AI and the proliferation of home feline health monitoring tools. 

The underserved feline health market represents a massive missed opportunity. According to CATalyst Council, the U.S. feline veterinary market has the potential to grow 2.5 times to US$32 billion if feline medicalisation matched that of dogs.

In a wide-ranging interview with Feline Business Brief, Ayers outlined:

  • Why the feline medicalisation gap persists;

  • Where AI will genuinely move the needle for cats; 

  • Why innovations in behaviour assessment, litter data, calming technologies, and decision-support tools will especially help felines.

Key insights from our interview

1. The feline medicalisation gap: Four entrenched barriers

Ayers began by pointing out a stark discrepancy underpinning the state of feline health today: “Less than one-third of cats in households go to the vet in any one year - that's a U.S. number - compared to over two-thirds of dogs in households.”

The CATalyst Council defines this as the “feline medicalisation gap.”

At the same time, Ayers noted: “The fact is that felines benefit from care, no less than canines. Their issues are different because, simple concept, they're different species.”

According to IDEXX data, the average age of cats at death / euthanasia has increased from 12.3 years in 2010 to 14.4 years in 2024 (an 18% increase). Dogs showed a smaller improvement, from 11.6 years to 13.4 years (16% increase).

Average patient lifespan trends 2010-2024. Data from IDEXX Practice Intelligence, based on an analysis of 2 million canine and feline patient records with documented deaths under the care of a veterinarian.

Entrenched factors behind the feline medicalisation gap

Cats hide disease more effectively:

  • As both predator and prey, cats have evolved to mask weakness.

  • “[Cats] hide their disease so they don't look weak and vulnerable as an easy meal. As a result, pet owners who aren't around them every minute of the day don't notice the disease,” Ayers said.

The stress factor:

  • “It is stressful for the cat and the caregiver, and, quite frankly, the veterinarian, to bring the cat to the vet,” Ayers said. This is a significant deterrent.

Price sensitivity:

  • Ayers noted emerging data suggesting feline households are more price-sensitive than canine ones.

  • This shapes veterinary behaviour: “Vets don’t always offer… and sometimes actively discourage… things like preventative diagnostics for cats.”

  • Cat caregivers are also more cost-conscious than dog owners.

Veterinarian discomfort and training gaps:

  • Despite cats being the second-most common companion species, many vets in the USA are less at ease examining them. 

  • U.S. veterinary education has been historically dog-centric.

  • Feline diseases, from hyperthyroidism to chronic kidney disease, are different, complex, and often less familiar.

Veterinarian-reported challenges working with cats vs. dogs (CATalyst Council, State of the Cat 2024)

These four factors have created decades-long structural barriers to care for cats. AI, Ayers argued, is about to unwind each one.

2. AI will address all four barriers faster than expected

Sylvester.ai

A. Behavioural AI and at-home monitoring will reduce missed illness

Ayers sees emerging home behaviour assessment technologies as the first major shift. These include Sylvester.ai, which uses AI to assess pain in cats’ facial expressions (which Ayers invested in last week), smart litter boxes, health trackers, smart feeders and water fountains.

“How cats behave in the home is much more natural and comfortable. You can learn a lot about the history of the cat that you would never know without technology such as Sylvester.ai and other related technologies,” Ayers said.

Health signals such as elimination frequency, water intake, weight trends can prompt the cat caregiver to seek veterinary care earlier.

B. Calming technologies help reduce feline stress

Pet Acoustics

Ayers also highlighted calming innovations such as Pet Acoustics’ species-specific music, as well as other approaches such as pheromones and medicinal relaxants.

The idea is straightforward: a calmer cat leads to a more confident vet, which in turn leads to a better exam and a higher likelihood of return visits.

C. AI-enabled price transparency may reshape the U.S. veterinary market

Veterinary service inflation has exceeded general inflation by > 60% in the consumer price index over the past two decades.

Ayers believes that AI-powered price comparison platforms will put competitive pressure on practices. The first clinics that publish or promote prices will draw clients, putting pressure on others to follow.

“It only takes 10% to 20% of the market to push another 60% into following along, because otherwise they suffer a further decline in their clientele,” he said.

D. Decision-support AI will raise vets’ confidence, especially with cats.

Ayers pointed out how large language models (LLMs) already produce high-quality differential diagnoses, highlight comorbidities, flag overlooked data points, and outline next steps more systematically than most humans can.

AI as a decision support tool disproportionately benefits felines because that's the area that vets feel most insecure. When you use a good prompt or a curated decision support tool, they're pretty good.

Jon Ayers

3. Why feline diagnostics are at an inflection point

Ayers believes that feline health is seeing the kind of inflection point that canine care saw years ago:

  • More feline-specific diagnostics

  • Increasing therapeutic options (especially for chronic diseases)

  • The rise of at-home behavioural insight

  • Stronger economic incentives for vets to embrace feline clients

  • And a pet industry realisation that cats are the underserved growth engine.

This moment did not exist during his tenure at IDEXX Laboratories, he adds. The shift began around 2019 and has accelerated dramatically since 2022.

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4. What to invest in

Ayers is bullish on:

  • Chronic kidney disease innovation

  • Hyperthyroidism diagnostics

  • Feline cancer detection

  • Cardiac disease

  • Obesity and metabolic conditions

  • Enrichment and robotics

  • Behavioural AI

  • Next-gen carriers, fountains, automated feeders

  • And any device that integrates structured data.

5. The personal motivation behind the mission

Ayers supports 41 types of felines, from wild cats to housecats.

We ended the conversation on a personal note. When asked what draws him to felines so much, Ayers replied:

“I can’t explain it. God told me to take care of cats.”

Ayers now supports 41 types of felines, chairs Panthera, and contributes to local trap-neuter-release (TNR), rehabilitation and health initiatives.

Key takeaway

AI alone will not “fix” feline health. It will, however, reduce the practical frictions that have held back feline access to veterinary care for decades.

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A story of resilience and leadership

Jon and his wife Helaine have committed US$20 million to The Ayers Wild Cat Conservation Trust.

Jon Ayers was Chairman, President and CEO of IDEXX Laboratories from 2002 to 2019, overseeing its transformation into a global veterinary diagnostics leader and growing revenues from US$380 million to US$2.4 billion.

In 2019, a devastating cycling accident left Ayers quadriplegic. Instead of stepping away, he redirected his energy toward conservation, philanthropy, and continued strategic work. His journey offers a rare example of tremendous resilience and leadership.

With deep experience across diagnostics, software, therapeutics and industry consolidation, Ayers brings a deep understanding of where veterinary medicine has come from, and where it’s headed. He holds an MBA from Harvard Business School and a degree in Molecular Biophysics and Biochemistry from Yale.

Stayed tuned for Part 2, which comes out this Friday.

Thanks for reading! Here's a friendly feline face for you. 😺

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